To our surprise, for several of these subcategories exenatide and sitagliptin apparently significantly reduced the odds ratios, in the case of exenatide, for example, regarding lung cancer, prostate cancer, lymphoma/multiple myeloma, metastasising tumors of unknown origin, and other tumours not specified. Sitagliptin significantly reduced the odds ratios for colon cancer, prostate cancer, and other tumours not specified. On the other hand, with exenatide treatment the rate of reporting carcinoid and stromal tumors and tumors of the female genital tract was apparently significantly elevated, and with sitagliptin treatment leukemias appeared to be reported significantly more often
For example, peptides that promote mitochondrial function in ovarian cells can increase local ATP and assist steroid enzymes to function more efficiently
This story has been updated to reflect the change.
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GH and IGF-1 directly affect growth plates